Flight Leonardo da Vinci–Fiumicino Airport departs from Rome Leonardo da Vinci–Fiumicino Airport at 15:30 and arrives at Istanbul Istanbul Atatürk Airport at 19:15.
The flighttime is about 2h 45m. The distance travelled ("as the bird flies"): 1844 Km. So the average speed is roughly 671 Km.
There is an 1 hour time difference between Rome and Istanbul