Below you can find the flight schedule for Houston to Chicago for May. If you are looking for flight fares, please check the cheap flights Houston to Chicago, or you can use the search form at the top.
| Airline | Flight number | Departure | Arrival | Flight time |
| Alaska Airlines | AS469 | 12:40 | 15:40 | 3h 0m |
| Lufthansa | LH7493 | 15:20 | 16:59 | 1h 39m |
| Lufthansa | LH7533 | 20:00 | 22:28 | 2h 28m |
| Lufthansa | LH2200 | 21:40 | 22:55 | 1h 15m |
| Spirit Airlines | NK200 | 06:10 | 07:37 | 1h 27m |
| Spirit Airlines | NK500 | 14:30 | 17:14 | 2h 44m |
| Spirit Airlines | NK821 | 16:04 | 18:43 | 2h 39m |
| Swiss Int Air Lines | LX1286 | 05:40 | 08:15 | 2h 35m |
| United Airlines | UA1215 | 00:55 | 06:02 | 5h 7m |
| United Airlines | UA713 | 01:55 | 08:40 | 6h 45m |
| United Airlines | UA2653 | 05:00 | 07:49 | 2h 49m |
| United Airlines | UA2195 | 05:00 | 07:48 | 2h 48m |
| United Airlines | UA764 | 05:00 | 07:45 | 2h 45m |
| United Airlines | UA469 | 05:30 | 08:04 | 2h 34m |
| United Airlines | UA1982 | 06:00 | 09:14 | 3h 14m |
| United Airlines | UA467 | 06:15 | 08:43 | 2h 28m |
| United Airlines | UA453 | 06:28 | 09:16 | 2h 48m |
| United Airlines | UA1236 | 06:45 | 09:33 | 2h 48m |
| United Airlines | UA556 | 06:57 | 13:16 | 6h 19m |
| United Airlines | UA1253 | 07:00 | 09:34 | 2h 34m |
| United Airlines | UA247 | 07:00 | 09:40 | 2h 40m |
| United Airlines | UA1168 | 07:05 | 11:06 | 4h 1m |
| United Airlines | UA2361 | 07:20 | 09:04 | 1h 44m |
| United Airlines | UA1578 | 07:30 | 10:18 | 2h 48m |
| United Airlines | UA2237 | 07:30 | 09:02 | 1h 32m |
| United Airlines | UA1941 | 07:31 | 08:50 | 1h 19m |
| United Airlines | UA1538 | 07:55 | 08:51 | 56m |
| United Airlines | UA2200 | 08:00 | 11:14 | 3h 14m |
| United Airlines | UA1752 | 08:00 | 09:39 | 1h 39m |
| United Airlines | UA1873 | 08:00 | 15:43 | 7h 43m |
| United Airlines | UA1946 | 08:05 | 10:53 | 2h 48m |
| United Airlines | UA1478 | 08:10 | 13:24 | 5h 14m |
| United Airlines | UA2406 | 08:30 | 09:44 | 1h 14m |
| United Airlines | UA503 | 09:00 | 11:49 | 2h 49m |
| United Airlines | UA520 | 09:05 | 17:47 | 8h 42m |
| United Airlines | UA2282 | 09:30 | 12:10 | 2h 40m |
| United Airlines | UA2425 | 09:59 | 13:05 | 3h 6m |
| United Airlines | UA2182 | 10:02 | 12:51 | 2h 49m |
| United Airlines | UA1009 | 11:15 | 13:00 | 1h 45m |
| United Airlines | UA715 | 11:51 | 13:53 | 2h 2m |
| United Airlines | UA624 | 12:10 | 14:55 | 2h 45m |
| United Airlines | UA2289 | 12:38 | 14:30 | 1h 52m |
| United Airlines | UA1989 | 14:00 | 18:09 | 4h 9m |
| United Airlines | UA1899 | 14:09 | 16:54 | 2h 45m |
| United Airlines | UA1611 | 14:10 | 15:44 | 1h 34m |
| United Airlines | UA2420 | 15:00 | 16:35 | 1h 35m |
| United Airlines | UA637 | 17:15 | 20:06 | 2h 51m |
| United Airlines | UA2463 | 17:50 | 23:24 | 5h 34m |
| United Airlines | UA1789 | 20:20 | 23:03 | 2h 43m |
| United Airlines | UA787 | 20:24 | 23:00 | 2h 36m |
Cheap flights Houston to Chicago.
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