Flight Vnukovo International Airport departs from Moscow Vnukovo International Airport at 11:45 and arrives at Tashkent International Airport at 17:30.
The flighttime is about 3h 45m. The distance travelled ("as the bird flies"): 3664 Km. So the average speed is roughly 977 Km.
There is an 2 hour time difference between Moscow and Tashkent