Flight Guarulhos International Airport departs from Sao Paulo Guarulhos International Airport at 20:40 and arrives at Rome Leonardo da Vinci–Fiumicino Airport at 12:00.
The flighttime is about 10h 20m. The distance travelled ("as the bird flies"): 9189 Km. So the average speed is roughly 889 Km.
There is an 5 hour time difference between Sao Paulo and Rome