Flight George Bush Intercontinental Airport departs from Houston George Bush Intercontinental Airport at 11:56 and arrives at Panama City Tocumen International Airport at 17:07.
The flighttime is about 4h 11m. The distance travelled ("as the bird flies"): 1748 Km. So the average speed is roughly 418 Km.
There is an 1 hour time difference between Houston and Panama City
