Please be aware that Milan has multiple airports and that these results are only for Milan Malpensa Airport.
The best day to arrive at Milan is Monday and it would be best to avoid Friday, as prices are on average 63.06% higher than on Monday. (Average prices, based on 212 datapoints.)
From Milan most of the flights depart to Amsterdam, second best connected from Milan is Athens. (Daily flights, based on 65 datapoints.)