Flight La Guardia Airport departs from New York La Guardia Airport at 20:00 and arrives at Chicago O'Hare International Airport at 07:21.The flight has a short stop at Dallas.
The flighttime is about 12h 21m. The distance travelled ("as the bird flies"): 1560 Km. So the average speed is roughly 126 Km.
There is an 1 hour time difference between New York and Chicago