Flight Brisbane Airport departs from Brisbane Brisbane Airport at 17:55 and arrives at Melbourne Melbourne Airport at 20:20.
The flighttime is about 2h 25m. The distance travelled ("as the bird flies"): 1343 Km. So the average speed is roughly 556 Km.
The best day to arrive at Brisbane is Saturday and it would be best to avoid Wednesday, as prices are on average 67.78% higher than on Saturday. (Average prices, based on 1661240 datapoints.)
We have a lot more statistics for flights VA 346 and between Brisbane and Melbourne.
