Flight Adolfo Suárez Madrid–Barajas Airport departs from Madrid Adolfo Suárez Madrid–Barajas Airport at 06:10 and arrives at Istanbul Istanbul Atatürk Airport at 12:30.
The flighttime is about 5h 20m. The distance travelled ("as the bird flies"): 3601 Km. So the average speed is roughly 675 Km.
There is an 1 hour time difference between Madrid and Istanbul