Flight Istanbul Atatürk Airport departs from Istanbul Istanbul Atatürk Airport at 17:35 and arrives at Rome Leonardo da Vinci–Fiumicino Airport at 18:15.
The flighttime is about 1h 40m. The distance travelled ("as the bird flies"): 1844 Km. So the average speed is roughly 1106 Km.
There is an 1 hour time difference between Istanbul and Rome