Please be aware that Melbourne has multiple airports and that these results are for all airports serving the city.
The best month to fly between Melbourne and Brisbane is January and the most expensive month to fly is October. (Average prices, based on 409 datapoints.)
The best day to arrive at Melbourne is Wednesday and it would be best to avoid Saturday, as prices are on average 187.81% higher than on Wednesday. (Average prices, based on 418 datapoints.)
The cheapest airline flying from Melbourne to Brisbane is JetStar Airways. They are 42% cheaper than Qantas. (Average prices, based on 444 datapoints.)
The best time to fly is at around 21. (Average prices, based on 791 datapoints.)