Flight Leonardo da Vinci–Fiumicino Airport departs from Rome Leonardo da Vinci–Fiumicino Airport at 05:45 and arrives at Catania Catania / Fontanarossa Airport at 07:05.
The flighttime is about 1h 20m. The distance travelled ("as the bird flies"): 564 Km. So the average speed is roughly 423 Km.