Flight Amsterdam Airport Schiphol departs from Amsterdam Amsterdam Airport Schiphol at 07:40 and arrives at Madrid Adolfo Suárez Madrid–Barajas Airport at 10:15.
The flighttime is about 2h 35m. The distance travelled ("as the bird flies"): 1606 Km. So the average speed is roughly 622 Km.
The best day to arrive at Amsterdam is Friday and it would be best to avoid Thursday, as prices are on average 298.13% higher than on Friday. (Average prices, based on 628968 datapoints.)
We have a lot more statistics for flights KL 1501 and between Amsterdam and Madrid.