Please be aware that Melbourne has multiple airports and that these results are for all airports serving the city.
The best month to fly between Melbourne and Adelaide is January and the most expensive month to fly is September. (Average prices, based on 1412 datapoints.)
The best day to arrive at Melbourne is Tuesday and it would be best to avoid Friday, as prices are on average 50.97% higher than on Tuesday. (Average prices, based on 1456 datapoints.)
The cheapest airline flying from Melbourne to Adelaide is JetStar Airways. They are 55% cheaper than Qantas. (Average prices, based on 1430 datapoints.)
The best time to fly is at around 6. (Average prices, based on 2352 datapoints.)