Flight Leonardo da Vinci–Fiumicino Airport departs from Rome Leonardo da Vinci–Fiumicino Airport at 20:00 and arrives at Catania Catania / Fontanarossa Airport at 21:15.
The flighttime is about 1h 15m. The distance travelled ("as the bird flies"): 564 Km. So the average speed is roughly 451 Km.