Flight Ben Gurion International Airport departs from Tel Aviv Ben Gurion International Airport at 18:15 and arrives at Rome Leonardo da Vinci–Fiumicino Airport at 21:00.
The flighttime is about 3h 45m. The distance travelled ("as the bird flies"): 2704 Km. So the average speed is roughly 721 Km.
There is an 1 hour time difference between Tel Aviv and Rome