Flight Istanbul Atatürk Airport departs from Istanbul Istanbul Atatürk Airport at 12:45 and arrives at Rome Leonardo da Vinci–Fiumicino Airport at 14:30.
The flighttime is about 2h 45m. The distance travelled ("as the bird flies"): 1844 Km. So the average speed is roughly 671 Km.
There is an 1 hour time difference between Istanbul and Rome