Flight Leonardo da Vinci–Fiumicino Airport departs from Rome Leonardo da Vinci–Fiumicino Airport at 11:10 and arrives at Lisbon Humberto Delgado Airport at 13:20.
The flighttime is about 3h 10m. The distance travelled ("as the bird flies"): 2401 Km. So the average speed is roughly 758 Km.
There is an 1 hour time difference between Rome and Lisbon