The best month to fly between Amsterdam and Istanbul is March and the most expensive month to fly is July. (Average prices, based on 1119 datapoints.)
The best day to arrive at Amsterdam is Monday and it would be best to avoid Friday, as prices are on average 41.62% higher than on Monday. (Average prices, based on 1119 datapoints.)
The cheapest airline flying from Amsterdam to Istanbul is ValuAir. They are 47% cheaper than KLM. (Average prices, based on 1130 datapoints.)
The best time to fly is at around 16. (Average prices, based on 2033 datapoints.)