The best month to fly between Amsterdam and Istanbul is March and the most expensive month to fly is July. (Average prices, based on 1101 datapoints.)
The best day to arrive at Amsterdam is Monday and it would be best to avoid Friday, as prices are on average 42.77% higher than on Monday. (Average prices, based on 1089 datapoints.)
The cheapest airline flying from Amsterdam to Istanbul is Pegasus Airlines. They are 76% cheaper than KLM. (Average prices, based on 1108 datapoints.)
The best time to fly is at around 7. (Average prices, based on 2143 datapoints.)