Please be aware that Istanbul has multiple airports and that these results are for all airports serving the city.
The best month to fly between Istanbul and Amsterdam is February and the most expensive month to fly is August. (Average prices, based on 741 datapoints.)
The best day to arrive at Istanbul is Monday and it would be best to avoid Saturday, as prices are on average 83.96% higher than on Monday. (Average prices, based on 741 datapoints.)
The best time to fly is at around 9. (Average prices, based on 1331 datapoints.)