Please be aware that Rome has multiple airports and that these results are for all airports serving the city.
The best month to arrive at Rome is July and the most expensive month to fly is April. (Average prices, based on 850 datapoints.)
The best day to arrive at Rome is Wednesday and it would be best to avoid Saturday, as prices are on average 42.75% higher than on Wednesday. (Average prices, based on 723 datapoints.)
The cheapest airline flying to Rome is Vueling. They are 94% cheaper than Singapore Airlines. (Average prices, based on 860 datapoints.)
At Rome the most flights depart around 17:00. (Hourly flights, based on 869 datapoints.)