Please be aware that Rome has multiple airports and that these results are for all airports serving the city.
The best day to arrive at Rome is Wednesday and it would be best to avoid Saturday, as prices are on average 64.75% higher than on Wednesday. (Average prices, based on 656 datapoints.)
The cheapest airline flying to Rome is Vueling. They are 72% cheaper than SA Express. (Average prices, based on 276 datapoints.)
At Rome the most flights depart around 11:00. (Hourly flights, based on 373 datapoints.)
From Rome it is on average the cheapest to fly to Eindhoven and to Brussels. (Average prices, based on 310 datapoints.)
From Rome most of the flights depart to Milan, second best connected from Rome is Munich. (Daily flights, based on 71 datapoints.)