Please be aware that Rome has multiple airports and that these results are for all airports serving the city.
The best month to arrive at Rome is January and the most expensive month to fly is May. (Average prices, based on 560 datapoints.)
The best day to arrive at Rome is Wednesday and it would be best to avoid Sunday, as prices are on average 50.61% higher than on Wednesday. (Average prices, based on 1995 datapoints.)
The cheapest airline flying to Rome is TAP Portugal. They are 79% cheaper than KLM. (Average prices, based on 655 datapoints.)
At Rome the most flights depart around 15:00. (Hourly flights, based on 958 datapoints.)
From Rome it is on average the cheapest to fly to Milan and to Barcelona. (Average prices, based on 285 datapoints.)
From Rome most of the flights depart to London, second best connected from Rome is Milan. (Daily flights, based on 138 datapoints.)