Please be aware that Rome has multiple airports and that these results are for all airports serving the city.
The best month to arrive at Rome is January and the most expensive month to fly is April. (Average prices, based on 700 datapoints.)
The best day to arrive at Rome is Wednesday and it would be best to avoid Saturday, as prices are on average 46.88% higher than on Wednesday. (Average prices, based on 720 datapoints.)
The cheapest airline flying to Rome is Vueling. They are 78% cheaper than Air France. (Average prices, based on 794 datapoints.)
At Rome the most flights depart around 15:00. (Hourly flights, based on 981 datapoints.)
From Rome it is on average the cheapest to fly to Brussels and to Paris. (Average prices, based on 346 datapoints.)
From Rome most of the flights depart to Paris, second best connected from Rome is Frankfurt. (Daily flights, based on 89 datapoints.)