Please be aware that Rome has multiple airports and that these results are for all airports serving the city.
The best month to arrive at Rome is January and the most expensive month to fly is April. (Average prices, based on 735 datapoints.)
The best day to arrive at Rome is Wednesday and it would be best to avoid Saturday, as prices are on average 46.88% higher than on Wednesday. (Average prices, based on 720 datapoints.)
The cheapest airline flying to Rome is Vueling. They are 79% cheaper than Lufthansa. (Average prices, based on 811 datapoints.)
At Rome the most flights depart around 17:00. (Hourly flights, based on 848 datapoints.)